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flc resistant strain  (ATCC)


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    ATCC flc resistant strain
    Flc Resistant Strain, supplied by ATCC, used in various techniques. Bioz Stars score: 99/100, based on 982 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/flc resistant strain/product/ATCC
    Average 99 stars, based on 982 article reviews
    flc resistant strain - by Bioz Stars, 2026-02
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    Effect of preincubation of C. albicans strain B311 with 25 μg of <t>FLC/ml</t> for 18 h before the fungus was exposed to 1.5 μg <t>of</t> <t>AMB/ml,</t> 25 μg of FLC/ml, or the combination of FLC and AMB. Transient resistance to AMB was seen in organisms that were preincubated with FLC and subsequently exposed to AMB, but this resistance was persistent for yeast that was subsequently exposed to the combination of FLC and AMB. O-OO, control; O-AO, sequential incubation of yeast in drug-free media followed by AMB; O-OF, preincubation in drug-free media and then FLC; O-AF, sequential incubation of yeast in drug-free media and then in media containing both AMB and FLC; F-OO, preincubation with FLC followed by drug-free media; F-AO, preincubation with FLC followed by AMB; F-OF, sequential incubation of yeast in FLC and then transfer of organisms to fresh media also containing FLC; F-AF, preincubation with FLC followed by treatment with AMB and FLC together.
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    Effect of preincubation of C. albicans strain B311 with 25 μg of FLC/ml for 18 h before the fungus was exposed to 1.5 μg of AMB/ml, 25 μg of FLC/ml, or the combination of FLC and AMB. Transient resistance to AMB was seen in organisms that were preincubated with FLC and subsequently exposed to AMB, but this resistance was persistent for yeast that was subsequently exposed to the combination of FLC and AMB. O-OO, control; O-AO, sequential incubation of yeast in drug-free media followed by AMB; O-OF, preincubation in drug-free media and then FLC; O-AF, sequential incubation of yeast in drug-free media and then in media containing both AMB and FLC; F-OO, preincubation with FLC followed by drug-free media; F-AO, preincubation with FLC followed by AMB; F-OF, sequential incubation of yeast in FLC and then transfer of organisms to fresh media also containing FLC; F-AF, preincubation with FLC followed by treatment with AMB and FLC together.

    Journal:

    Article Title: Impact of the Order of Initiation of Fluconazole and Amphotericin B in Sequential or Combination Therapy on Killing of Candida albicans In Vitro and in a Rabbit Model of Endocarditis and Pyelonephritis

    doi: 10.1128/AAC.45.2.485-494.2001

    Figure Lengend Snippet: Effect of preincubation of C. albicans strain B311 with 25 μg of FLC/ml for 18 h before the fungus was exposed to 1.5 μg of AMB/ml, 25 μg of FLC/ml, or the combination of FLC and AMB. Transient resistance to AMB was seen in organisms that were preincubated with FLC and subsequently exposed to AMB, but this resistance was persistent for yeast that was subsequently exposed to the combination of FLC and AMB. O-OO, control; O-AO, sequential incubation of yeast in drug-free media followed by AMB; O-OF, preincubation in drug-free media and then FLC; O-AF, sequential incubation of yeast in drug-free media and then in media containing both AMB and FLC; F-OO, preincubation with FLC followed by drug-free media; F-AO, preincubation with FLC followed by AMB; F-OF, sequential incubation of yeast in FLC and then transfer of organisms to fresh media also containing FLC; F-AF, preincubation with FLC followed by treatment with AMB and FLC together.

    Article Snippet: For animals that received AMB and FLC in combination, AMB concentrations in serum were measured using a FLC-resistant C. albicans strain ( B59630 ; gift of F. Odds, Janssen Research Foundation, Beerse, Belgium) in the biological assay.

    Techniques: Control, Incubation

    Effect of FLC preincubation on the activity of AMB for C. albicans strains 6 (A), ATCC 36082 (B), and 95–1939 (C). The abbreviations are defined in the legend to Fig. ​Fig.11.

    Journal:

    Article Title: Impact of the Order of Initiation of Fluconazole and Amphotericin B in Sequential or Combination Therapy on Killing of Candida albicans In Vitro and in a Rabbit Model of Endocarditis and Pyelonephritis

    doi: 10.1128/AAC.45.2.485-494.2001

    Figure Lengend Snippet: Effect of FLC preincubation on the activity of AMB for C. albicans strains 6 (A), ATCC 36082 (B), and 95–1939 (C). The abbreviations are defined in the legend to Fig. ​Fig.11.

    Article Snippet: For animals that received AMB and FLC in combination, AMB concentrations in serum were measured using a FLC-resistant C. albicans strain ( B59630 ; gift of F. Odds, Janssen Research Foundation, Beerse, Belgium) in the biological assay.

    Techniques: Activity Assay

    Impact of the duration of fluconazole preincubation on the activity of AMB for C. albicans B311. Yeast were incubated with 25 μg of FLC/ml for 0, 16, or 40 h and subsequently transferred to media containing 25 μg of FLC (F)/ml, drug-free media, or 1.5 μg of AMB (A)/ml. 0hr F-O, 0hr F-A, and 0hr F-F: yeast incubated in drug-free media (control), AMB, and FLC, respectively, without preincubation in drug-containing media. 16hr F-O, 16hr F-A, 16hr F-F: yeast incubated for 16 h in 25 μg of FLC/ml prior to incubation in drug-free media, AMB, or FLC. 40hr F-O, 40hr F-A, and 40hr F-F: yeast incubated in 25 μg of FLC/ml for 40 h before incubation in drug-free media, AMB, and FLC, respectively.

    Journal:

    Article Title: Impact of the Order of Initiation of Fluconazole and Amphotericin B in Sequential or Combination Therapy on Killing of Candida albicans In Vitro and in a Rabbit Model of Endocarditis and Pyelonephritis

    doi: 10.1128/AAC.45.2.485-494.2001

    Figure Lengend Snippet: Impact of the duration of fluconazole preincubation on the activity of AMB for C. albicans B311. Yeast were incubated with 25 μg of FLC/ml for 0, 16, or 40 h and subsequently transferred to media containing 25 μg of FLC (F)/ml, drug-free media, or 1.5 μg of AMB (A)/ml. 0hr F-O, 0hr F-A, and 0hr F-F: yeast incubated in drug-free media (control), AMB, and FLC, respectively, without preincubation in drug-containing media. 16hr F-O, 16hr F-A, 16hr F-F: yeast incubated for 16 h in 25 μg of FLC/ml prior to incubation in drug-free media, AMB, or FLC. 40hr F-O, 40hr F-A, and 40hr F-F: yeast incubated in 25 μg of FLC/ml for 40 h before incubation in drug-free media, AMB, and FLC, respectively.

    Article Snippet: For animals that received AMB and FLC in combination, AMB concentrations in serum were measured using a FLC-resistant C. albicans strain ( B59630 ; gift of F. Odds, Janssen Research Foundation, Beerse, Belgium) in the biological assay.

    Techniques: Activity Assay, Incubation, Control

    Effect of FLC preincubation on the activity of low-concentration AMB (0.5 μg/ml) for C. albicans B311. The abbreviations are defined in the legend to Fig. ​Fig.11.

    Journal:

    Article Title: Impact of the Order of Initiation of Fluconazole and Amphotericin B in Sequential or Combination Therapy on Killing of Candida albicans In Vitro and in a Rabbit Model of Endocarditis and Pyelonephritis

    doi: 10.1128/AAC.45.2.485-494.2001

    Figure Lengend Snippet: Effect of FLC preincubation on the activity of low-concentration AMB (0.5 μg/ml) for C. albicans B311. The abbreviations are defined in the legend to Fig. ​Fig.11.

    Article Snippet: For animals that received AMB and FLC in combination, AMB concentrations in serum were measured using a FLC-resistant C. albicans strain ( B59630 ; gift of F. Odds, Janssen Research Foundation, Beerse, Belgium) in the biological assay.

    Techniques: Activity Assay, Concentration Assay

    Pharmacokinetics of FLC (42.4 mg/kg per day) (A) and AMB (1.0 mg/kg per day) (B), given i.v., in sera of infected rabbits at steady state.

    Journal:

    Article Title: Impact of the Order of Initiation of Fluconazole and Amphotericin B in Sequential or Combination Therapy on Killing of Candida albicans In Vitro and in a Rabbit Model of Endocarditis and Pyelonephritis

    doi: 10.1128/AAC.45.2.485-494.2001

    Figure Lengend Snippet: Pharmacokinetics of FLC (42.4 mg/kg per day) (A) and AMB (1.0 mg/kg per day) (B), given i.v., in sera of infected rabbits at steady state.

    Article Snippet: For animals that received AMB and FLC in combination, AMB concentrations in serum were measured using a FLC-resistant C. albicans strain ( B59630 ; gift of F. Odds, Janssen Research Foundation, Beerse, Belgium) in the biological assay.

    Techniques: Drug discovery, Infection

    Serial levels of creatinine and BUN in serum measured in infected rabbits treated with various antifungal drug regimens for up to 13 days a

    Journal:

    Article Title: Impact of the Order of Initiation of Fluconazole and Amphotericin B in Sequential or Combination Therapy on Killing of Candida albicans In Vitro and in a Rabbit Model of Endocarditis and Pyelonephritis

    doi: 10.1128/AAC.45.2.485-494.2001

    Figure Lengend Snippet: Serial levels of creatinine and BUN in serum measured in infected rabbits treated with various antifungal drug regimens for up to 13 days a

    Article Snippet: For animals that received AMB and FLC in combination, AMB concentrations in serum were measured using a FLC-resistant C. albicans strain ( B59630 ; gift of F. Odds, Janssen Research Foundation, Beerse, Belgium) in the biological assay.

    Techniques: Infection, Control

    Trough concentrations of drugs in sera of infected rabbits after 5 and 13 days of treatment with various antifungal drug regimens

    Journal:

    Article Title: Impact of the Order of Initiation of Fluconazole and Amphotericin B in Sequential or Combination Therapy on Killing of Candida albicans In Vitro and in a Rabbit Model of Endocarditis and Pyelonephritis

    doi: 10.1128/AAC.45.2.485-494.2001

    Figure Lengend Snippet: Trough concentrations of drugs in sera of infected rabbits after 5 and 13 days of treatment with various antifungal drug regimens

    Article Snippet: For animals that received AMB and FLC in combination, AMB concentrations in serum were measured using a FLC-resistant C. albicans strain ( B59630 ; gift of F. Odds, Janssen Research Foundation, Beerse, Belgium) in the biological assay.

    Techniques: Infection

    Density of C. albicans in cardiac vegetations of rabbits that received 5, 13, and 21 days of antifungal drug therapy a

    Journal:

    Article Title: Impact of the Order of Initiation of Fluconazole and Amphotericin B in Sequential or Combination Therapy on Killing of Candida albicans In Vitro and in a Rabbit Model of Endocarditis and Pyelonephritis

    doi: 10.1128/AAC.45.2.485-494.2001

    Figure Lengend Snippet: Density of C. albicans in cardiac vegetations of rabbits that received 5, 13, and 21 days of antifungal drug therapy a

    Article Snippet: For animals that received AMB and FLC in combination, AMB concentrations in serum were measured using a FLC-resistant C. albicans strain ( B59630 ; gift of F. Odds, Janssen Research Foundation, Beerse, Belgium) in the biological assay.

    Techniques: Control

    Density of C. albicans in kidneys of rabbits that received 2, 5, 13, and 21 days of antifungal drug therapy a

    Journal:

    Article Title: Impact of the Order of Initiation of Fluconazole and Amphotericin B in Sequential or Combination Therapy on Killing of Candida albicans In Vitro and in a Rabbit Model of Endocarditis and Pyelonephritis

    doi: 10.1128/AAC.45.2.485-494.2001

    Figure Lengend Snippet: Density of C. albicans in kidneys of rabbits that received 2, 5, 13, and 21 days of antifungal drug therapy a

    Article Snippet: For animals that received AMB and FLC in combination, AMB concentrations in serum were measured using a FLC-resistant C. albicans strain ( B59630 ; gift of F. Odds, Janssen Research Foundation, Beerse, Belgium) in the biological assay.

    Techniques: Control

    Effect of using FLC treatment for 1 or 5 days prior to switching to AMB+FLC or AMB on C. albicans density in cardiac vegetations and kidneys

    Journal:

    Article Title: Impact of the Order of Initiation of Fluconazole and Amphotericin B in Sequential or Combination Therapy on Killing of Candida albicans In Vitro and in a Rabbit Model of Endocarditis and Pyelonephritis

    doi: 10.1128/AAC.45.2.485-494.2001

    Figure Lengend Snippet: Effect of using FLC treatment for 1 or 5 days prior to switching to AMB+FLC or AMB on C. albicans density in cardiac vegetations and kidneys

    Article Snippet: For animals that received AMB and FLC in combination, AMB concentrations in serum were measured using a FLC-resistant C. albicans strain ( B59630 ; gift of F. Odds, Janssen Research Foundation, Beerse, Belgium) in the biological assay.

    Techniques: